Human Engineered Heart Tissue: Analysis of Contractile Force

Ingra Mannhardt, Kaja Breckwoldt, David Letuffe-Brenière, +14

Stem Cell Reports

Tissue EngineeringCardiac MuscleEngineeringBiofabricationBiomedical Engineering +20

Functional improvement and maturation of rat and human engineered heart tissue by chronic electrical stimulation

Marc N. Hirt, Jasper Boeddinghaus, Alice N. Mitchell, +12

Journal of Molecular and Cellular Cardiology

Tissue EngineeringCardiac MuscleEngineeringMature EhtFunctional Improvement +21

Differentiation of cardiomyocytes and generation of human engineered heart tissue

Kaja Breckwoldt, David Letuffe-Brenière, Ingra Mannhardt, +18

Nature Protocols

Regenerative MedicineTissue EngineeringCardiac MuscleCardiomyopathyDevelopmental Biology +12

Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density

Marc D. Lemoine, Ingra Mannhardt, Kaja Breckwoldt, +12

Scientific Reports

Low Resting Membrane Potential and Low Inward Rectifier Potassium Currents Are Not Inherent Features of hiPSC-Derived Cardiomyocytes

András Horváth, Marc D. Lemoine, Alexandra Löser, +13

Stem Cell Reports

Automated analysis of contractile force and Ca²⁺transients in engineered heart tissue

Andrea Stoehr, Christiane Neuber, Christina Baldauf, +12

American Journal of Physiology-Heart and Circulatory Physiology

Tissue EngineeringCardiac MuscleHeart FailureEngineeringMyofilament Ca +18

Heterozygous LmnadelK32 mice develop dilated cardiomyopathy through a combined pathomechanism of haploinsufficiency and peptide toxicity

Marie‐Elodie Cattin, A. Bertrand, Saskia Schlossarek, +14

Human Molecular Genetics

Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue

Alexandra Eder, Arne Hansen, June Uebeler, +7

Basic Research in Cardiology

Cardiac MuscleHeart FailureRelaxation TimeCardiovascular PharmacologyPharmacotherapy +22

Guanabenz Interferes with ER Stress and Exerts Protective Effects in Cardiac Myocytes

Christiane Neuber, June Uebeler, Thomas G. Schulze, +3

PLoS ONE

Cardiac MuscleHeart FailureCardiovascular PharmacologyCell DeathEr Stress +22

Common MicroRNA Signatures in Cardiac Hypertrophic and Atrophic Remodeling Induced by Changes in Hemodynamic Load

Ali El‐Armouche, Alexander Peter Schwoerer, Christiane Neuber, +7

PLoS ONE