Lin Yang

Pembrolizumab plus chemotherapy versus placebo plus chemotherapy for HER2-negative advanced gastric cancer (KEYNOTE-859): a multicentre, randomised, double-blind, phase 3 trial

Sun Young Rha, Do‐Youn Oh, Patricio Yañez et al. · The Lancet Oncology · 2023 · 521 citations

Chemotherapy Versus Placebo, Gastrointestinal Oncology, Medicine +8

A Phase I, Multicenter, Open-Label, First-in-Human, Dose-Escalation Study of the Oral Smoothened Inhibitor Sonidegib (LDE225) in Patients with Advanced Solid Tumors

Jordi Rodón, Hussein Tawbi, Anne Thomas et al. · Clinical Cancer Research · 2014 · 228 citations · Full text

Phase I dose-escalation study of the protein kinase C (PKC) inhibitor AEB071 in patients with metastatic uveal melanoma.

Sophie Piperno‐Neumann, Ellen Kapiteijn, James Larkin et al. · Journal of Clinical Oncology · 2014 · 54 citations

Immunology, Immunotherapeutics, Dermatology +17

Safety, pharmacokinetics, and pharmacodynamics of the DR5 antibody LBY135 alone and in combination with capecitabine in patients with advanced solid tumors

Sunil Sharma, Elisabeth G.E. de Vries, Jeffrey R. Infante et al. · Investigational New Drugs · 2013 · 52 citations

Oncology, Medicine, Advanced Solid Tumors +7

Comparison of Mismatch Repair Status Between Primary and Matched Metastatic Sites in Patients With Colorectal Cancer

Wenzhuo He, Wan-Ming Hu, Fang Wang et al. · Journal of the National Comprehensive Cancer Network · 2019 · 45 citations · Full text