Hardik J. Patel

The epichaperome is an integrated chaperome network that facilitates tumour survival

Anna Rodina, Tai Wang, Pengrong Yan et al. · Nature · 2016 · 293 citations · Full text

Tumor Biology, Medicine, Natural Sciences +10

Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2

Pallav D. Patel, Pengrong Yan, Paul M. Seidler et al. · Nature Chemical Biology · 2013 · 211 citations · Full text

Tumor Biology, Medicine, Paralog-selective Hsp90 Inhibitors +4

Experimental and Structural Testing Module to Analyze Paralogue-Specificity and Affinity in the Hsp90 Inhibitors Series

Tony Taldone, Pallav D. Patel, Maulik Patel et al. · Journal of Medicinal Chemistry · 2013 · 77 citations · Full text

Drug Target, Molecular Biology, Hsp90 Inhibitors Series +19

Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

Pengrong Yan, Hardik J. Patel, Sahil Sharma et al. · Cell Reports · 2020 · 59 citations · Full text

Glycobiology, Molecular Biology, Aberrant N-glycosylation +21

Heat Shock Protein 70 Inhibitors. 1. 2,5′-Thiodipyrimidine and 5-(Phenylthio)pyrimidine Acrylamides as Irreversible Binders to an Allosteric Site on Heat Shock Protein 70

Yanlong Kang, Tony Taldone, Hardik J. Patel et al. · Journal of Medicinal Chemistry · 2014 · 58 citations · Full text