Cara East

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial

David E. Kandzari, Michael Böhm, Felix Mahfoud et al. · The Lancet · 2018 · 776 citations

Medicine, Cardiology, Pharmacology +11

Catheter-based renal denervation in patients with uncontrolled hypertension in the absence of antihypertensive medications (SPYRAL HTN-OFF MED): a randomised, sham-controlled, proof-of-concept trial

Raymond R. Townsend, Felix Mahfoud, David E. Kandzari et al. · The Lancet · 2017 · 734 citations

Medicine, Cardiology, Nephrology +10

Efficacy of catheter-based renal denervation in the absence of antihypertensive medications (SPYRAL HTN-OFF MED Pivotal): a multicentre, randomised, sham-controlled trial

Michael Böhm, Kazuomi Kario, David E. Kandzari et al. · The Lancet · 2020 · 587 citations

Medicine, Cardiology, Nephrology +8

Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial

Kausik K Ray, Helen M Colhoun, Michael Szarek et al. · The Lancet Diabetes & Endocrinology · 2019 · 328 citations · Full text

Medicine, Cardiology, Internal Medicine +15

Long-term efficacy and safety of renal denervation in the presence of antihypertensive drugs (SPYRAL HTN-ON MED): a randomised, sham-controlled trial

Felix Mahfoud, David E. Kandzari, Kazuomi Kario et al. · The Lancet · 2022 · 282 citations · Full text

Medicine, Cardiology, Nephrology +11