Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder

Michael J. Gandal, Pan Zhang, Evi Hadjimichael, +185

Science

Psychiatric DisordersGeneticsGenetic EpidemiologyNeurochemical BiomarkersDisease Gene Identification +20

Comprehensive functional genomic resource and integrative model for the human brain

Daifeng Wang, Shuang Liu, Jonathan Warrell, +190

Science

NeurogenomicsGeneticsGenetic EpidemiologyBrain MappingSocial Sciences +24

Transcriptome and epigenome landscape of human cortical development modeled in organoids

Anahita Amiri, Gianfilippo Coppola, Soraya Scuderi, +144

Science

Brain DevelopmentGeneticsNeurodevelopmentEpigenome LandscapeCerebral Organoid +22

Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk

Prashanth Rajarajan, Tyler Borrman, Will Liao, +21

Science

Brain DevelopmentGeneticsEpigeneticsSocial SciencesPsychiatric Genetics +19

Perspectives on ENCODE

Federico Abascal, Reyes Acosta, Nicholas J. Addleman, +514

Nature

Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment

Marc F. Lensink, Sameer Velankar, Andriy Kryshtafovych, +99

Proteins Structure Function and Bioinformatics

Structural BioinformaticsBiomolecular Structure PredictionMolecular BiologyProtein DockingAnalytical Ultracentrifugation +15

Liquid chromatin Hi-C characterizes compartment-dependent chromatin interaction dynamics

Houda Belaghzal, Tyler Borrman, Andrew D. Stephens, +5

Nature Genetics

ChromatinChromatin RemodelingNatural SciencesEpigenomicsMolecular Biology +5

Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment

Marc F. Lensink, Guillaume Brysbaert, Nurul Nadzirin, +102

Proteins Structure Function and Bioinformatics

Structural BioinformaticsBiomolecular Structure PredictionMolecular BiologyCapri Round 46Protein Folding +14

Genome-wide mapping of human DNA replication by optical replication mapping supports a stochastic model of eukaryotic replication

Weitao Wang, Kyle N. Klein, Karel Proesmans, +9

Molecular Cell

ChromatinGenome InstabilityHuman Dna ReplicationDna SequencingNatural Sciences +10

Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders

Benxia Hu, Hyejung Won, Won Mah, +153

Nature Communications

Gene Regulatory LandscapeGeneticsCerebral OrganoidGlial 3DCellular Neurobiology +20