Jason Flamm

Severe CD4⁺T-Cell Depletion in Gut Lymphoid Tissue during Primary Human Immunodeficiency Virus Type 1 Infection and Substantial Delay in Restoration following Highly Active Antiretroviral Therapy

Moraima Guadalupe, Elizabeth Reay, Sumathi Sankaran et al. · Journal of Virology · 2003 · 861 citations · Full text

Substantial Delay, Immunodeficiencies, T-regulatory Cell +20

Dolutegravir plus lamivudine versus dolutegravir plus tenofovir disoproxil fumarate and emtricitabine in antiretroviral-naive adults with HIV-1 infection (GEMINI-1 and GEMINI-2): week 48 results from two multicentre, double-blind, randomised, non-inferiority, phase 3 trials

Pedro Cahn, Juan Sierra Madero, José Ramón Arribas et al. · The Lancet · 2018 · 371 citations · Full text

Hiv/aids Counselling, Treatment And Prevention, Week 48 +14

Viral Suppression and Immune Restoration in the Gastrointestinal Mucosa of Human Immunodeficiency Virus Type 1-Infected Patients Initiating Therapy during Primary or Chronic Infection

Moraima Guadalupe, Sumathi Sankaran, Michael D. George et al. · Journal of Virology · 2006 · 251 citations · Full text

Chronic Hiv Infection, Immunology, Immune Restoration +17

Effective CD4+ T-cell restoration in gut-associated lymphoid tissue of HIV-infected patients is associated with enhanced Th17 cells and polyfunctional HIV-specific T-cell responses

Mónica Macal, Sumathi Sankaran, T-W Chun et al. · Mucosal Immunology · 2008 · 203 citations

Inflammation, Autoimmune Disease, Enhanced Th17 Cells +13

Rapid Onset of Intestinal Epithelial Barrier Dysfunction in Primary Human Immunodeficiency Virus Infection Is Driven by an Imbalance between Immune Response and Mucosal Repair and Regeneration

Sumathi Sankaran, Michael D. George, Elizabeth Reay et al. · Journal of Virology · 2007 · 199 citations · Full text

Rapid Onset, Immune Regulation, Immunology +19