Huw Thomas

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Claire Palles, Jean‐Baptiste Cazier, Kimberley Howarth et al. · Nature Genetics · 2012 · 1K citations · Full text

Life Sciences, Genetics, Oncology +14

Long-term effect of aspirin on cancer risk in carriers of hereditary colorectal cancer: an analysis from the CAPP2 randomised controlled trial

John Burn, Anne‐Marie Gerdes, Finlay Macrae et al. · The Lancet · 2011 · 951 citations · Full text

Medicine, Oncology, Pharmacotherapy +16

Multiple Colorectal Adenomas, Classic Adenomatous Polyposis, and Germ-Line Mutations in<i>MYH</i>

Oliver M. Sieber, Lara Lipton, Michael Crabtree et al. · New England Journal of Medicine · 2003 · 860 citations

Life Sciences, Genetics, Molecular Genetics +17

A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21

Ian Tomlinson, Emily L. Webb, Luis G. Carvajal‐Carmona et al. · Nature Genetics · 2007 · 809 citations

Life Sciences, Genetics, Molecular Genetics +14

Revised guidelines for the clinical management of Lynch syndrome (HNPCC): recommendations by a group of European experts

Hans F. A. Vasen, Ignacio Blanco, Katja Aktan–Collan et al. · Gut · 2013 · 744 citations · Full text

Medicine, Cardiology, Internal Medicine +7