Niek Dekker

Thermofluor-based high-throughput stability optimization of proteins for structural studies

U.B. Ericsson, B.M. Hallberg, George T. DeTitta et al. · Analytical Biochemistry · 2006 · 843 citations

Life Sciences, Biochemistry, Biophysics +10

Crystal structure of the outer membrane protease OmpT from Escherichia coli suggests a novel catalytic site

Lucy Vandeputte-Rutten, Reinhard Krämer, Jan Kroon et al. · The EMBO Journal · 2001 · 273 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

Selection of Fluorescent, Bioluminescent, and Radioactive Tracers to Accurately Reflect Extracellular Vesicle Biodistribution <i>in Vivo</i>

Elisa Lázaro‐Ibáñez, Farid N. Faruqu, Amer F. Saleh et al. · ACS Nano · 2021 · 264 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Structural insight into allosteric modulation of protease-activated receptor 2

R.K. Cheng, Cédric Fiez-Vandal, Oliver Schlenker et al. · Nature · 2017 · 253 citations

Life Sciences, Biochemistry, Molecular Biology +16

Structural evidence for dimerization-regulated activation of an integral membrane phospholipase

Iban Ubarretxena‐Belandia, Mieke Blaauw, K.H. Kalk et al. · Nature · 1999 · 229 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15