Microbial short-chain fatty acids modulate CD8+ T cell responses and improve adoptive immunotherapy for cancer

Maik Luu, Zeno Riester, Adrian Baldrich, +23

Nature Communications

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

Maik Luu, Sabine Pautz, Vanessa Kohl, +16

Nature Communications

Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation

Nadine Bollig, Anne Brüstle, Kerstin Kellner, +16

Proceedings of the National Academy of Sciences

Microenvironmental Th9 and Th17 lymphocytes induce metastatic spreading in lung cancer

Ylia Salazar, Xiang Zheng, David Brunn, +20

Journal of Clinical Investigation

Immune MicroenvironmentLung InflammationImmunologyImmune RegulationBiological Microenvironments +14

Lactate induces metabolic and epigenetic reprogramming of pro‐inflammatory Th17 cells

Aleksandra Lopez Krol, Hannah P Nehring, Felix F. Krause, +12

EMBO Reports

InflammationInflammatory DiseaseImmune Cell DevelopmentMedicineImmunology +7

The transcription factor Interferon Regulatory Factor 4 is required for the generation of protective effector CD8 ⁺ T cells

Friederike Raczkowski, Josephine Ritter, Kira Heesch, +13

Proceedings of the National Academy of Sciences

Novel GM-CSF signals via IFN-γR/IRF-1 and AKT/mTOR license monocytes for suppressor function

Eliana Ribechini, James A. Hutchinson, Sabine Hergovits, +18

Blood Advances

IL-17+ CD8+ T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis

Christina Lückel, Felix S.R. Picard, Hartmann Raifer, +25

Nature Communications

Role of actin filaments in endothelial cell-cell adhesion and membrane stability under fluid shear stress

Hans‐Joachim Schnittler, Stefan W. Schneider, Hartmann Raifer, +4

Pflügers Archiv - European Journal of Physiology

MechanobiologyEngineeringFluid Shear StressCell AdhesionPhysiology +12

Prognosis of ovarian cancer is associated with effector memory CD8⁺ T cell accumulation in ascites, CXCL9 levels and activation-triggered signal transduction in T cells

Sonja Lieber, Silke Reinartz, Hartmann Raifer, +8

OncoImmunology