Brock Brown

Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11

Jing Li, Tanya Yakushi, Francesco Parlati et al. · Nature Chemical Biology · 2017 · 158 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Role of Corticotropin-Releasing Factor (CRF) Receptors in the Anorexic Syndrome Induced by CRF

Mary Ann Pelleymounter, Margaret Joppa, Michelle Carmouché et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 151 citations

Medicine, Endocrinology, Pharmacology +17

Discovery and Validation of a Series of Aryl Sulfonamides as Selective Inhibitors of Tissue-Nonspecific Alkaline Phosphatase (TNAP)

Russell Dahl, Eduard Sergienko, Ying Su et al. · Journal of Medicinal Chemistry · 2009 · 104 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

The Regulation of Feeding and Metabolic Rate and the Prevention of Murine Cancer Cachexia with a Small-Molecule Melanocortin-4 Receptor Antagonist

Stacy Markison, Alan C. Foster, Chen Chen et al. · Endocrinology · 2005 · 98 citations · Full text

Life Sciences, Pharmacology, Pharmacotherapy +17

Design and synthesis of pyrazole derivatives as potent and selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP)

Shyama Sidique, Robert Ardecky, Ying Su et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 84 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11