Nicotine reinforcement and cognition restored by targeted expression of nicotinic receptors

Uwe Maskos, Brian E. Molles, Sebastián Pons, +16

Nature

Tobacco CessationTobacco ControlCognitive ScienceNicotine ReinforcementTobacco Use +12

Distinct contributions of nicotinic acetylcholine receptor subunit α4 and subunit α6 to the reinforcing effects of nicotine

Richard Exley, Nicolas Maubourguet, Vincent David, +11

Proceedings of the National Academy of Sciences

Synaptic TransmissionNeurotransmitterNeurotransmissionSocial SciencesMolecular Pharmacology +17

Long-term effects of chronic nicotine exposure on brain nicotinic receptors

Morgane Besson, Sylvie Granon, Monica Mameli-Engvall, +7

Proceedings of the National Academy of Sciences

Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: Dependence on cholinergic nicotinic and dopaminergic D1 receptors

Vincent David, Morgane Besson, Jean‐Pierre Changeux, +2

Neuropharmacology

NeurophysiologyBehavioral NeuroscienceNeuroanatomyPhysiologyNicotine Microinjections +10

Genetic dissociation of two behaviors associated with nicotine addiction: Beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome

Morgane Besson, Vincent David, Sandra Suárez, +4

Psychopharmacology

Tobacco ControlSubstance AbuseBehavioral SciencesNicotine ReinforcementPsychiatry +12

Differential effects of the dopamine D 2 /D 3 receptor antagonist sulpiride on self-administration of morphine into the ventral tegmental area or the nucleus accumbens

Vincent David, Thomas Durkin, Pierre Cazala

Psychopharmacology

Dopamine D 2PsychiatryBehavioral NeuroscienceAddictionReceptor Antagonist Sulpiride +11

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice

Morgane Besson, Vincent David, Mathieu Baudonnat, +7

Psychopharmacology

Alpha7-nicotinic ReceptorsAddictionExtracellular Dopamine OutflowPhysiologyMedicine +10

Self-administration of morphine into the lateral hypothalamus in the mouse

Pierre Cazala, Christian Darracq, Michel Saint-Marc

Brain Research

Psychoactive DrugNeurophysiologyNeuroanatomyBehavioral NeuroscienceHypothalamus +13

Modulation of anxiety by μ-opioid receptors of the lateral septal region in mice

Julie Le Merrer, Barbara Cagniard, Pierre Cazala

Pharmacology Biochemistry and Behavior

PsychiatryNeurophysiologyAffective NeurosciencePsychopharmacologyNeuropharmacology +9

Brain Regional Fos Expression Elicited by the Activation of μ- but not δ-Opioid Receptors of the Ventral Tegmental Area: Evidence for an Implication of the Ventral Thalamus in Opiate Reward

Vincent David, Audrey Matifas, Stéphanie Gavello-Baudy, +3

Neuropsychopharmacology

Neurobiological MechanismVentral ThalamusPsychiatryNeurophysiologyNeuroanatomy +12