Helene Pearlman

Pharmacokinetic Assessment of Drug‐Drug Interactions of Isavuconazole With the Immunosuppressants Cyclosporine, Mycophenolic Acid, Prednisolone, Sirolimus, and Tacrolimus in Healthy Adults

Andreas H. Groll, Amit Desai, David Han et al. · Clinical Pharmacology in Drug Development · 2016 · 130 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Pharmacokinetic Evaluation of CYP3A4‐Mediated Drug‐Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults

Robert Townsend, Albert G. H. Dietz, Christine Hale et al. · Clinical Pharmacology in Drug Development · 2016 · 111 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Isavuconazole absorption following oral administration in healthy subjects is comparable to intravenous dosing, and is not affected by food, or drugs that alter stomach pH

Anne Schmitt‐Hoffmann, Amit Desai, Donna Kowalski et al. · International Journal of Clinical Pharmacology and Therapeutics · 2016 · 83 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +17

Pharmacokinetic Effects of Isavuconazole Coadministration With the Cytochrome P450 Enzyme Substrates Bupropion, Repaglinide, Caffeine, Dextromethorphan, and Methadone in Healthy Subjects

Takao Yamazaki, Amit Desai, Ronald Goldwater et al. · Clinical Pharmacology in Drug Development · 2016 · 44 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

Pharmacokinetic and Pharmacodynamic Evaluation of the Drug‐Drug Interaction Between Isavuconazole and Warfarin in Healthy Subjects

Amit Desai, Takao Yamazaki, Albert J. Dietz et al. · Clinical Pharmacology in Drug Development · 2016 · 28 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17