George Kirov

The mutational constraint spectrum quantified from variation in 141,456 humans

Konrad J. Karczewski, Laurent C. Francioli, Grace Tiao et al. · Nature · 2020 · 9.6K citations · Full text

De novo mutations in schizophrenia implicate synaptic networks

Menachem Fromer, Andrew Pocklington, David H. Kavanagh et al. · Nature · 2014 · 1.7K citations · Full text

Synaptic Plasticity, Psychotic Disorder, Psychiatric Genetics +7

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Bjarni J. Vilhjálmsson, Jian Yang, Hilary K. Finucane et al. · The American Journal of Human Genetics · 2015 · 1.5K citations · Full text

Linkage Disequilibrium, Engineering, Polygenic Risk +4

Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

Phil H. Lee, Verneri Anttila, Hyejung Won et al. · Cell · 2019 · 1.4K citations · Full text

Psychiatry, Psychiatric Disorders, Genetic Disorder +15

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Pamela Sklar, Stephan Ripke, Laura J. Scott et al. · Nature Genetics · 2011 · 1.4K citations

Genome-wide Association Study, Genotype-phenotype Association, Psychiatry +8