Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant

Rigel Suzuki, Daichi Yamasoba, Izumi Kimura, +74

Nature

Gold Nanoparticles as a Vaccine Platform: Influence of Size and Shape on Immunological Responses <i>in Vitro</i> and <i>in Vivo</i>

Kenichi Niikura, Tatsuya Matsunaga, Tadaki Suzuki, +9

ACS Nano

NanoparticlesEngineeringImmunologyImmunodominanceVaccine Platform +19

Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19

Yuto Unoh, Shota Uehara, Kenji Nakahara, +22

Journal of Medicinal Chemistry

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike

Daichi Yamasoba, Izumi Kimura, Hesham Nasser, +47

Cell

VaccinationGlobal SpreadBa.2 Spike-bearing VirusViral PersistenceVaccine Development +12

The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice

Shigetomo Fukuhara, Szandor Simmons, Shunsuke Kawamura, +16

Journal of Clinical Investigation

Endothelial CellsT-regulatory CellImmunologyPathologyImmunologic Mechanism +20

Thymus-derived leukemia-lymphoma in mice transgenic for the Tax gene of human T-lymphotropic virus type I

Hideki Hasegawa, Hirofumi Sawa, Martha J. Lewis, +12

Nature Medicine

Lymphoid NeoplasiaImmunogeneticsTax GeneImmunologyPathology +7

RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells

Taisho Yamada, Seiichi Sato, Yuki Sotoyama, +5

Nature Immunology

Lung InflammationImmunologyAntiviral ResponseInfectious Respiratory DiseaseCovid-19 +3

SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells

Michihito Sasaki, Kentaro Uemura, Akihiko Sato, +6

PLoS Pathogens

S Gene MutationsSars-cov-2 VariantsViral EvolutionVirus VariantsMedicine +11

Forkhead Transcription Factor FoxO1 in Adipose Tissue Regulates Energy Storage and Expenditure

Jun Nakae, Yongheng Cao, Miyo Oki, +7

Diabetes

SARS-CoV-2 inhibits induction of the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis

Ji‐Seung Yoo, Michihito Sasaki, Steven Cho, +7

Nature Communications