Michelle Hiu-Wai Kung

Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)

Philip Wing‐Lok Ho, Chi-Ting Leung, Huifang Liu et al. · Autophagy · 2019 · 203 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Aberrant mitochondrial morphology and function associated with impaired mitophagy and DNM1L-MAPK/ERK signaling are found in aged mutant Parkinsonian LRRK2^R1441Gmice

Huifang Liu, Philip Wing‐Lok Ho, Chi-Ting Leung et al. · Autophagy · 2020 · 101 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

Mitochondrial UCP5 is neuroprotective by preserving mitochondrial membrane potential, ATP levels, and reducing oxidative stress in MPP+ and dopamine toxicity

Ken Hon‐Hung Kwok, Philip Wing‐Lok Ho, Andrew Chi‐Yuen Chu et al. · Free Radical Biology and Medicine · 2010 · 80 citations

Life Sciences, Neurobiology, Neuroscience +16

Mitochondrial UCP4 attenuates MPP+- and dopamine-induced oxidative stress, mitochondrial depolarization, and ATP deficiency in neurons and is interlinked with UCP2 expression

Andrew Chi‐Yuen Chu, Philip Wing‐Lok Ho, Ken Hon‐Hung Kwok et al. · Free Radical Biology and Medicine · 2008 · 73 citations

Life Sciences, Neurobiology, Neuroscience +12

Combined LRRK2 mutation, aging and chronic low dose oral rotenone as a model of Parkinson’s disease

Huifang Liu, Philip Wing‐Lok Ho, Gideon Chi-Ting Leung et al. · Scientific Reports · 2017 · 54 citations · Full text

Life Sciences, Neurology, Neuroscience +17