Haochen Xie

A Novel Approach Based on Gut Microbiota Analysis and Network Pharmacology to Explain the Mechanisms of Action of Cichorium intybus L. Formula in the Improvement of Hyperuricemic Nephropathy in Rats

Mukaram Amatjan, Na Li, Pengke He et al. · Drug Design Development and Therapy · 2023 · 37 citations · Full text

Medicine, Nephrology, Pharmacology +17

Integration of network pharmacology and intestinal flora to investigate the mechanism of action of Chinese herbal <i>Cichorium intybus</i> formula in attenuating adenine and ethambutol hydrochloride-induced hyperuricemic nephropathy in rats

Na Li, Mukaram Amatjan, Pengke He et al. · Pharmaceutical Biology · 2022 · 16 citations · Full text

Medicine, Nephrology, Pharmacology +10

Design, synthesis, and evaluation of n-butylphthalide and ligustrazine hybrids as potent neuroprotective agents for the treatment of ischemic stroke in vitro and in vivo

Yi Jia, Haiyan Xiao, Xiaolin Wang et al. · Bioorganic Chemistry · 2023 · 14 citations

Medicine, Medicinal Chemistry, Neuroscience +15

N-butylphthalide (NBP) and ligustrazine (TMP) triazole hybrids target the KEAP1-NRF2 pathway to inhibit ferroptosis and exert brain neuroprotectivity

Guangyu Li, Haiyan Xiao, Chenwei Zuo et al. · Redox Biology · 2025 · 11 citations · Full text

Medicine, Neuroscience, Pharmacology +13