Domenica A. Pizzi

Discovery Process and Pharmacological Characterization of 2-(<i>S</i>)-(4-Fluoro-2-methylphenyl)piperazine-1-carboxylic Acid [1-(<i>R</i>)-(3,5-Bis-trifluoromethylphenyl)ethyl]methylamide (Vestipitant) as a Potent, Selective, and Orally Active NK₁ Receptor Antagonist

Romano Di Fabio, Cristiana Griffante, Giuseppe Alvaro et al. · Journal of Medicinal Chemistry · 2009 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and Biological Characterization of (2<i>R</i>,4<i>S</i>)-1′-Acetyl-<i>N</i>-{(1<i>R</i>)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl}-2-(4-fluoro-2-methylphenyl)-<i>N</i>-methyl-4,4′-bipiperidine-1-carboxamide as a New Potent and Selective Neurokinin 1 (NK₁) Receptor Antagonist Clinical Candidate

Romano Di Fabio, Giuseppe Alvaro, Cristiana Griffante et al. · Journal of Medicinal Chemistry · 2011 · 36 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Stereochemistry of the microbial generation of .delta.-decanolide, .gamma.-dodecanolide, and .gamma.-nonanolide from C18 13-hydroxy, C18 10-hydroxy, and C19 14-hydroxy unsaturated fatty acids

Rosanna Cardillo, Giovanni Fronza, Claudio Fuganti et al. · The Journal of Organic Chemistry · 1991 · 35 citations

Life Sciences, Biochemistry, Microbiology +12

Novel carbazole derivatives as NPY Y1 antagonists

Colin P. Leslie, Romano Di Fabio, Francesca Bonetti et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Synthesis and structure–activity relationship of N-(3-azabicyclo[3.1.0]hex-6-ylmethyl)-5-(2-pyridinyl)-1,3-thiazol-2-amines derivatives as NPY Y5 antagonists

Matteo Biagetti, Colin P. Leslie, Angelica Mazzali et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10