Owen M. Siggs

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

Jamie E. Craig, Xikun Han, Ayub Qassim et al. · Nature Genetics · 2020 · 360 citations · Full text

Life Sciences, Genetics, Ophthalmology +17

Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity

Tomokazu Souma, Stuart W. Tompson, Benjamin R. Thomson et al. · Journal of Clinical Investigation · 2016 · 289 citations · Full text

Medicine, Genetics, Ophthalmology +17

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

Stuart MacGregor, Jue‐Sheng Ong, Jiyuan An et al. · Nature Genetics · 2018 · 237 citations · Full text

Life Sciences, Genetics, Ophthalmology +11

Angiopoietin-1 is required for Schlemm’s canal development in mice and humans

Benjamin R. Thomson, Tomokazu Souma, Stuart W. Tompson et al. · Journal of Clinical Investigation · 2017 · 199 citations · Full text

Medicine, Molecular Genetics, Ophthalmology +17

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins

Delphine Mérino, Maybelline Giam, Peter Hughes et al. · The Journal of Cell Biology · 2009 · 184 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13