Owen M. Siggs

Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression

Jamie E. Craig, Xikun Han, Ayub Qassim et al. · Nature Genetics · 2020 · 339 citations · Full text

Genome-wide Association Study, Disease Susceptibility, Medicine +12

Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity

Tomokazu Souma, Stuart W. Tompson, Benjamin R. Thomson et al. · Journal of Clinical Investigation · 2016 · 286 citations · Full text

Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma

Stuart MacGregor, Jue‐Sheng Ong, Jiyuan An et al. · Nature Genetics · 2018 · 219 citations · Full text

Genome-wide Association Study, Transcriptional Regulation, Systems Biology +8

Angiopoietin-1 is required for Schlemm’s canal development in mice and humans

Benjamin R. Thomson, Tomokazu Souma, Stuart W. Tompson et al. · Journal of Clinical Investigation · 2017 · 196 citations · Full text

Ocular Disease, Schlemm ’, Cellular Physiology +18

The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins

Delphine Mérino, Maybelline Giam, Peter Hughes et al. · The Journal of Cell Biology · 2009 · 184 citations · Full text

Apoptosis, Immunology, Molecular Biology +18