Jaebon Lee

Inhibition of Glutamine Utilization Synergizes with Immune Checkpoint Inhibitor to Promote Antitumor Immunity

Jun‐Kyu Byun, Mihyang Park, Seunghyeong Lee et al. · Molecular Cell · 2020 · 202 citations · Full text

Life Sciences, Immunology, Oncology +16

Macropinocytosis is an alternative pathway of cysteine acquisition and mitigates sorafenib-induced ferroptosis in hepatocellular carcinoma

Jun‐Kyu Byun, Seunghyeong Lee, Gilwon Kang et al. · Journal of Experimental & Clinical Cancer Research · 2022 · 114 citations · Full text

Medicine, Oncology, Pharmacology +13

Oncogenic KRAS signaling activates mTORC1 through COUP‐TFII‐mediated lactate production

Jun‐Kyu Byun, Mihyang Park, Jae Won Yun et al. · EMBO Reports · 2019 · 38 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

DN200434, an orally available inverse agonist of estrogen-related receptor γ, induces ferroptosis in sorafenib-resistant hepatocellular carcinoma

Dongho Kim, Mi Jin Kim, Nayoung Kim et al. · BMB Reports · 2022 · 23 citations · Full text

Medicine, Oncology, Pharmacology +13

Glutamine-derived aspartate is required for eIF5A hypusination-mediated translation of HIF-1α to induce the polarization of tumor-associated macrophages

Dongho Kim, Yoo Na Kang, Jonghwa Jin et al. · Experimental & Molecular Medicine · 2024 · 22 citations · Full text

Medicine, Cancer Biology, Oncology +17