Paul H.M. Smits

Upfront Genotyping of <i>DPYD</i>*<i>2A</i> to Individualize Fluoropyrimidine Therapy: A Safety and Cost Analysis

Maarten J. Deenen, Didier Meulendijks, Annemieke Cats et al. · Journal of Clinical Oncology · 2015 · 333 citations · Full text

Relationship between Single Nucleotide Polymorphisms and Haplotypes in <i>DPYD</i> and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer

Maarten J. Deenen, Jolien Tol, Artur M Burylo et al. · Clinical Cancer Research · 2011 · 183 citations

Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide

Corine Ekhart, Valerie D. Doodeman, Sjoerd Rodenhuis et al. · Pharmacogenetics and Genomics · 2008 · 133 citations

HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53

Didier Meulendijks, N B Tomasoa, L. Dewit et al. · British Journal of Cancer · 2015 · 109 citations · Full text

Multi-centre evaluation of real-time multiplex PCR for detection of carbapenemase genes OXA-48, VIM, IMP, NDM and KPC

Anneke van der Zee, Lieuwe Roorda, Gerda Bosman et al. · BMC Infectious Diseases · 2014 · 107 citations · Full text