Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor)

Aurélie Thedrez, Dirk Blom, Stéphane Ramin‐Mangata, +11

Arteriosclerosis Thrombosis and Vascular Biology

PCSK9 inhibition with alirocumab reduces lipoprotein(a) levels in nonhuman primates by lowering apolipoprotein(a) production rate

Mikaël Croyal, Thi-Thu-Trang Tran, Rose Hélène Blanchard, +16

Clinical Science

A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove

Benny J. Evison, James T. Palmer, Gilles Lambert, +16

Bioorganic & Medicinal Chemistry

A high-throughput mass spectrometry-based assay for large-scale profiling of circulating human apolipoproteins

Valentin Blanchard, Damien Garçon, Catherine Jaunet, +15

Journal of Lipid Research

Kinetics of plasma apolipoprotein E isoforms by LC-MS/MS: a pilot study

Valentin Blanchard, Stéphane Ramin‐Mangata, Stéphanie Billon‐Crossouard, +12

Journal of Lipid Research

Lipoprotein(a) Cellular Uptake Ex Vivo and Hepatic Capture In Vivo Is Insensitive to PCSK9 Inhibition With Alirocumab

Kévin Chemello, Sandra Beeské, Thi Thu Trang Tran, +13

JACC Basic to Translational Science

The size of apolipoprotein (a) is an independent determinant of the reduction in lipoprotein (a) induced by PCSK9 inhibitors

Valentin Blanchard, Kévin Chemello, Tim Hollstein, +10

Cardiovascular Research

Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes

Mikaël Croyal, Matthieu Wargny, Kévin Chemello, +7

Cardiovascular Diabetology

A Novel, Orally Bioavailable, Small-Molecule Inhibitor of PCSK9 With Significant Cholesterol-Lowering Properties In Vivo

Alexandra K. Suchowerska, Geurt Stokman, James T. Palmer, +13

Journal of Lipid Research

Plasma Apolipoprotein Concentrations Are Highly Altered in Severe Intensive Care Unit COVID-19 Patients: Preliminary Results from the LIPICOR Cohort Study

Floran Bègue, Kévin Chemello, Bryan Veeren, +11

International Journal of Molecular Sciences

Acute Lung InjuryAbsolute Apolipoprotein ConcentrationsApolipoprotein LevelsHyperlipidemiaCovid-19 Epidemiology +15