Gino Van Heeke

Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A‐mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)

Simon J. MacKenzie, George S. Baillie, Ian McPhee et al. · British Journal of Pharmacology · 2002 · 258 citations · Full text

RNA Silencing Identifies PDE4D5 as the Functionally Relevant cAMP Phosphodiesterase Interacting with βArrestin to Control the Protein Kinase A/AKAP79-mediated Switching of the β2-Adrenergic Receptor to Activation of ERK in HEK293B2 Cells

Martin J. Lynch, George S. Baillie, Ahmed Mohamed et al. · Journal of Biological Chemistry · 2005 · 202 citations · Full text

Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats

Anton Bespalov, Ilya Sukhanov, Elena Blokhina et al. · Neuropharmacology · 2005 · 126 citations

Tobacco Control, Substance Abuse, Psychiatry +14

Differential expression of PDE4 cAMP phosphodiesterase isoforms in inflammatory cells of smokers with COPD, smokers without COPD, and nonsmokers

Rachael Barber, George S. Baillie, Reinhard Bergmann et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2004 · 118 citations

Asthma, Inflammatory Lung Disease, Advanced Lung Disease +17

Activity Profile of Dust Mite Allergen Extract Using Substrate Libraries and Functional Proteomic Microarrays

Jennifer L. Harris, Daniel E. Mason, Jun Li et al. · Chemistry & Biology · 2004 · 114 citations · Full text

Bioinformatics, Environmental Allergy, Molecular Characterization +11