N S Paranka

Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis.

Gary A. Piazza, Alanna L. Kulchak Rahm, Mary F. Krutzsch et al. · PubMed · 1995 · 434 citations

Tumor Biology, Medicinal Chemistry, Oncology +14

Sulindac sulfone inhibits azoxymethane-induced colon carcinogenesis in rats without reducing prostaglandin levels.

Gary A. Piazza, David S. Alberts, Lee J. Hixson et al. · PubMed · 1997 · 361 citations

Chemoprevention Strategy, Prostaglandin Levels, Gastrointestinal Pharmacology +16

Sulfone metabolite of sulindac inhibits mammary carcinogenesis.

Henry J. Thompson, Cheng Jiang, Junxuan Lü et al. · PubMed · 1997 · 210 citations

Cancer Metabolism, Sulfone Metabolite, Chemoprevention Strategy +12

Antiproliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells.

Lee J. Hixson, David S. Alberts, Mary F. Krutzsch et al. · PubMed · 1994 · 106 citations

Antiproliferative Effect, Anti-inflammatory, Medicine +12

Do NSAIDs exert their colon cancer chemoprevention activities through the inhibition of mucosal prostaglandin synthetase?

David S. Alberts, Lee J. Hixson, Dennis J. Ahnen et al. · Journal of Cellular Biochemistry · 1995 · 100 citations

Prostaglandin Precursors, Anti-inflammatory, Oncology +14