Karen Dorso

Platensimycin is a selective FabF inhibitor with potent antibiotic properties

Jun Wang, S.M. Soisson, Katherine Young et al. · Nature · 2006 · 809 citations

Antibiotics, Medicine, Pharmacotherapy +11

Discovery of platencin, a dual FabF and FabH inhibitor with <i>in vivo</i> antibiotic properties

Jun Wang, Srinivas Kodali, Sang Ho Lee et al. · Proceedings of the National Academy of Sciences · 2007 · 380 citations · Full text

Bioorganic Chemistry, Engineering, Antibiotic Adjuvant +20

Discovery of a Small Molecule That Inhibits Cell Division by Blocking FtsZ, a Novel Therapeutic Target of Antibiotics

Jun Wang, Andrew Galgoci, Srinivas Kodali et al. · Journal of Biological Chemistry · 2003 · 195 citations · Full text

Discovery of Kibdelomycin, A Potent New Class of Bacterial Type II Topoisomerase Inhibitor by Chemical-Genetic Profiling in Staphylococcus aureus

John W. Phillips, Michael Goetz, Scott K. Smith et al. · Chemistry & Biology · 2011 · 163 citations

Antimicrobial Susceptibility, Chemical-genetic Profiling, Medicine +10

Chemical Genetic Identification of Peptidoglycan Inhibitors Potentiating Carbapenem Activity against Methicillin-Resistant Staphylococcus aureus

Joann Huber, Robert G. K. Donald, Sang Ho Lee et al. · Chemistry & Biology · 2009 · 112 citations

Methicillin-resistant Staphylococcus Aureus, Health Sciences, Antimicrobial Susceptibility +12