MicroRNA-146a protects against cognitive decline induced by surgical trauma by suppressing hippocampal neuroinflammation in mice

Lei Chen, Rui Dong, Yayuan Lu, +4

Brain Behavior and Immunity

InflammationMolecular NeuroscienceMedicineHippocampal NeuroinflammationMicrorna-146a Protects +11

Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes

Haowen Qiao, Moujian Guo, Jia Shang, +7

PLoS Pathogens

Brain DevelopmentNeurological DisorderImmunologyViral PathogenesisCerebral Organoid +19

Surgery/Anesthesia disturbs mitochondrial fission/fusion dynamics in the brain of aged mice with postoperative delirium

Yayuan Lu, Lei Chen, Jishi Ye, +5

Aging

Postoperative DeliriumMitochondrial Fission/fusion DynamicsMitochondrial DysfunctionGeriatric AnesthesiaDynamic Balance +17

17β-estradiol prevents cardiac diastolic dysfunction by stimulating mitochondrial function: A preclinical study in a mouse model of a human hypertrophic cardiomyopathy mutation

Youzhou Chen, Zhuoli Zhang, Fenghuan Hu, +7

The Journal of Steroid Biochemistry and Molecular Biology

Cardiac MuscleCardiomyopathyMolecular PhysiologyCardiovascular DiseaseMitochondrial Function +10

Netrin-1 Ameliorates Postoperative Delirium-Like Behavior in Aged Mice by Suppressing Neuroinflammation and Restoring Impaired Blood-Brain Barrier Permeability

Ke Li, Jiayu Wang, Lei Chen, +4

Frontiers in Molecular Neuroscience

Cholecystokinin octapeptide improves hippocampal glutamatergic synaptogenesis and postoperative cognition by inhibiting induction of A1 reactive astrocytes in aged mice

Lei Chen, Ning Yang, Yue Li, +12

CNS Neuroscience & Therapeutics

Fraxetin attenuates ferroptosis in myocardial infarction via AKT/Nrf2/HO-1 signaling.

Yifei Xu, Haiyan Lin, Huan Wang, +2

PubMed

Astragaloside Alleviates Hepatic Fibrosis Function via PAR2 Signaling Pathway in Diabetic Rats

Zhenchang Wang, Quanqiang Li, Mingpeng Xiang, +4

Cellular Physiology and Biochemistry

Toll-like receptor 2 in promoting angiogenesis after acute ischemic injury

Yifei Xu, Ying Zhou, Haiyan Lin, +3

International Journal of Molecular Medicine

ImmunologyCell DeathToll-like Receptor 2InflammationAngiogenesis +16

Ferric-loaded lipid nanoparticles inducing ferroptosis-like cell death for antibacterial wound healing

Ying Zhou, Chongyang Cai, Cheng Wang, +5

Drug Delivery