Control of Viremia and Prevention of Clinical AIDS in Rhesus Monkeys by Cytokine-Augmented DNA Vaccination

Dan H. Barouch, Sampa Santra, Jörn E. Schmitz, +26

Science

Eventual AIDS vaccine failure in a rhesus monkey by viral escape from cytotoxic T lymphocytes

Dan H. Barouch, Jennifer Kunstman, Marcelo J. Kuroda, +11

Nature

VaccinationCytotoxic T LymphocytesVaccine DevelopmentVaccine TargetHuman Retrovirus +7

Viral Escape from Dominant Simian Immunodeficiency Virus Epitope-Specific Cytotoxic T Lymphocytes in DNA-Vaccinated Rhesus Monkeys

Dan H. Barouch, Jennifer Kunstman, Jennifer Glowczwskie, +12

Journal of Virology

Primary ImmunodeficiencyViral ReplicationSystems BiologyPlasma Viral RnaDominant Epitope-specific Ctl +11

Replication-Defective Adenovirus Serotype 5 Vectors Elicit Durable Cellular and Humoral Immune Responses in Nonhuman Primates

Sampa Santra, Michael S. Seaman, Ling Xu, +13

Journal of Virology

Humoral Immune ResponsesVaccine ModalityViral PathogenesisImmunologyPlasmid Dna-primed Monkeys +18

Heterologous Envelope Immunogens Contribute to AIDS Vaccine Protection in Rhesus Monkeys

Norman L. Letvin, Yue Huang, Bimal K. Chakrabarti, +15

Journal of Virology

ImmunologyHiv-1 Env ImmunogenImmunotherapyRhesus MonkeysChallenge Virus +16

Multiclade Human Immunodeficiency Virus Type 1 Envelope Immunogens Elicit Broad Cellular and Humoral Immunity in Rhesus Monkeys

Michael S. Seaman, Ling Xu, Kristin Beaudry, +11

Journal of Virology

Pathogenicity of Simian-Human Immunodeficiency Virus SHIV-89.6P and SIVmac Is Attenuated in Cynomolgus Macaques and Associated with Early T-Lymphocyte Responses

Keith A. Reimann, Robert A. Parker, Michael S. Seaman, +9

Journal of Virology

ImmunologyViral PathogenesisPathologyCynomolgus MacaquesSivmac Is Attenuated +14

Neutralizing Antibodies Elicited by Immunization of Monkeys with DNA Plasmids and Recombinant Adenoviral Vectors Expressing Human Immunodeficiency Virus Type 1 Proteins

John R. Mascola, Anna Sambor, Kristin Beaudry, +12

Journal of Virology

Viral ReplicationImmunologyAntiviral DrugImmunotherapyDna Plasmids +15

Cellular Immunity Elicited by Human Immunodeficiency Virus Type 1/ Simian Immunodeficiency Virus DNA Vaccination Does Not Augment the Sterile Protection Afforded by Passive Infusion of Neutralizing Antibodies

John R. Mascola, Mark G. Lewis, Thomas C. VanCott, +15

Journal of Virology

Neutralizing AntibodiesImmunologyImmunotherapyHuman RetrovirusSterile Protection Afforded +15

Role of Genes That Modulate Host Immune Responses in the Immunogenicity and Pathogenicity of Vaccinia Virus

Shawn S. Jackson, Petr O. Ilyinskii, Valérie Philippon, +10

Journal of Virology

Humoral ResponseImmunologyHost ResponseVaccine TargetViral Genetics +14