Minimizing Oxidation and Stable Nanoscale Dispersion Improves the Biocompatibility of Graphene in the Lung

Matthew C. Duch, G. R. Scott Budinger, Yu Liang, +8

Nano Letters

Acute Lung InjuryNanomedicineChemical EngineeringTissue EngineeringEngineering +11

Vimentin regulates activation of the NLRP3 inflammasome

Gimena dos Santos, Micah R. Rogel, Margaret Baker, +13

Nature Communications

Particulate matter air pollution causes oxidant-mediated increase in gut permeability in mice

Ece Mutlu, Phillip A. Engen, Saul Soberanes, +10

Particle and Fibre Toxicology

Biocompatible Nanoscale Dispersion of Single-Walled Carbon Nanotubes Minimizes in vivo Pulmonary Toxicity

Gökhan M. Mutlu, G. R. Scott Budinger, Alexander A. Green, +7

Nano Letters

PAI-1–regulated extracellular proteolysis governs senescence and survival in <i>Klotho</i> mice

Mesut Eren, Amanda E. Boe, Sheila B. Murphy, +9

Proceedings of the National Academy of Sciences

Mitochondrial Complex III-generated Oxidants Activate ASK1 and JNK to Induce Alveolar Epithelial Cell Death following Exposure to Particulate Matter Air Pollution

Saul Soberanes, Daniela Urich, Christina M. Baker, +12

Journal of Biological Chemistry

Lipid PeroxidationAir QualityCell DeathRedox BiologyOxidative Stress +15

β2-Adrenergic agonists augment air pollution–induced IL-6 release and thrombosis

Sergio E. Chiarella, Saul Soberanes, Daniela Urich, +15

Journal of Clinical Investigation

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmune RegulationImmunology +18

Epithelial Cell Death Is an Important Contributor to Oxidant-mediated Acute Lung Injury

G. R. Scott Budinger, Gökhan M. Mutlu, Daniela Urich, +14

American Journal of Respiratory and Critical Care Medicine

Particulate Matter-Induced Lung Inflammation Increases Systemic Levels of PAI-1 and Activates Coagulation Through Distinct Mechanisms

G. R. Scott Budinger, Joanne L. McKell, Daniela Urich, +12

PLoS ONE

Leptin Promotes Fibroproliferative Acute Respiratory Distress Syndrome by Inhibiting Peroxisome Proliferator–activated Receptor-γ

Manu Jain, G. R. Scott Budinger, Daniela Urich, +11

American Journal of Respiratory and Critical Care Medicine