Concepedia

Author

Valentina Molteni

Genomics Institute of the Novartis Research FoundationORCID

Also Known As

Molteni, V., Molteni, Valentina, V. MOLTENI, V. Molteni, Valentina Molteni

64

Publications

3.3K

Citations

30

H-Index

67

Concepts

All Affiliations

Genomics Institute of the Novartis Research FoundationNovartis (United States)University of California San DiegoUniversity of MilanNovartis (Switzerland)
VM

About

Valentina Molteni is an author at Genomics Institute of the Novartis Research Foundation specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

14

15

1.2K

2

Natural Sciences

10

10

1K

3

Engineering

8

8

315

4

Biochemistry

6

6

453

5

Health Sciences

1

1

57

Valentina Molteni

×

37

Publications

2.9K

Citations

27

H-Index

YearCitations

The nuclear receptor LXR is a glucose sensor

Nico Mitro, Puiying A. Mak, Leo Vargas,

Nature

2006

512

Proteasome inhibition for treatment of leishmaniasis, Chagas disease and sleeping sickness

Shilpi Khare, A. S. Nagle, Agnes Biggart,

Nature

2016

407

Discovery of Tropifexor (LJN452), a Highly Potent Non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH)

David C. Tully, Paul V. Rucker, D. CHIANELLI,

Journal of Medicinal Chemistry

2017

224

One-Pot Electrochemical Nickel-Catalyzed Decarboxylative Sp<sup>2</sup>–Sp<sup>3</sup> Cross-Coupling

Takaoki Koyanagi, Ananda Herath, Ashley Chong,

Organic Letters

2019

113

Discovery and Characterization of Clinical Candidate LXE408 as a Kinetoplastid-Selective Proteasome Inhibitor for the Treatment of Leishmaniases

A. S. Nagle, Agnes Biggart, C. Be,

Journal of Medicinal Chemistry

2020

111

Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis

D. CHIANELLI, Paul V. Rucker, Jason Roland,

Journal of Medicinal Chemistry

2020

97

Discovery of GNF-5837, a Selective TRK Inhibitor with Efficacy in Rodent Cancer Tumor Models

Pam Albaugh, Yi Fan, Yuan Mi,

ACS Medicinal Chemistry Letters

2012

95

Tropifexor‐Mediated Abrogation of Steatohepatitis and Fibrosis Is Associated With the Antioxidative Gene Expression Profile in Rodents

Eloy D. Hernandez, Lianxing Zheng, Young Ho Kim,

Hepatology Communications

2019

88

Identification of a small-molecule binding site at the dimer interface of the HIV integrase catalytic domain

Valentina Molteni, Jason Greenwald, Denise Rhodes,

Acta Crystallographica Section D Biological Crystallography

2001

87

Aqueous One-Pot Synthesis of Pyrazoles, Pyrimidines and Isoxazoles Promoted by Microwave Irradiation

Valentina Molteni, Matthew M. Hamilton, Long Mao,

Synthesis

2002

87

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