Jacek Majewski

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.6K citations

Chromatin, Neuro-oncology, Chromatin Structure +13

Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma

Dominik Sturm, Hendrik Witt, Volker Hovestadt et al. · Cancer Cell · 2012 · 1.8K citations · Full text

Neuro-oncology, Radiation Oncology, Somatic Variant +11

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

Dong-Anh Khuong-Quang, Pawel Buczkowicz, Patricia Rakopoulos et al. · Acta Neuropathologica · 2012 · 988 citations · Full text

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

David Jones, Barbara Hutter, Natalie Jäger et al. · Nature Genetics · 2013 · 814 citations · Full text

Neuro-oncology, Molecular Neuroscience, Glioma +7

De novo germline and postzygotic mutations in AKT3, PIK3R2 and PIK3CA cause a spectrum of related megalencephaly syndromes

Jean-Baptiste Rivière, Ghayda Mirzaa, Brian J. O’Roak et al. · Nature Genetics · 2012 · 737 citations · Full text

Mendelian Disorder, Genetic Disorder, Medicine +11