Marnix H. P. de Groot

EGFR activation limits the response of liver cancer to lenvatinib

Haojie Jin, Yuanyuan Lv, Shengxian Yuan et al. · Nature · 2021 · 432 citations

Medicine, Oncology, Pharmacology +14

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance

Leila Akkari, Robert L. Bowman, Jeremy Tessier et al. · Science Translational Medicine · 2020 · 322 citations

Medicine, Immunology, Oncology +17

CD103+ regulatory T cells underlie resistance to radio-immunotherapy and impair CD8+ T cell activation in glioblastoma

Luuk van Hooren, Shanna M. Handgraaf, Daan J. Kloosterman et al. · Nature Cancer · 2023 · 98 citations · Full text

Medicine, Immunology, Oncology +17

Cancer cell genetics shaping of the tumor microenvironment reveals myeloid cell-centric exploitable vulnerabilities in hepatocellular carcinoma

Christel Ramirez, Daniel Taranto, Masami Ando‐Kuri et al. · Nature Communications · 2024 · 35 citations · Full text

Medicine, Immunology, Oncology +17

Rational combination of <scp>SHP2</scp> and <scp>mTOR</scp> inhibition for the treatment of hepatocellular carcinoma

Antonio Mulero‐Sánchez, Christel Ramirez, Aimée du Chatinier et al. · Molecular Oncology · 2023 · 14 citations · Full text

Medicine, Oncology, Pharmacology +17