Lazaro Lorenzo

Autoantibodies against type I IFNs in patients with life-threatening COVID-19

Paul Bastard, Lindsey B. Rosen, Qian Zhang et al. · Science · 2020 · 2.8K citations · Full text

Viral Diagnostics, Immunodeficiencies, Viral Immunity +19

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

Qian Zhang, Paul Bastard, Zhiyong Liu et al. · Science · 2020 · 2.4K citations · Full text

Human Loci, Disease Susceptibility, Inborn Errors +14

TLR3 Deficiency in Patients with Herpes Simplex Encephalitis

Shen‐Ying Zhang, Emmanuelle Jouanguy, Sophie Ugolini et al. · Science · 2007 · 1.1K citations

Human Tlr3, Innate Immune System, Immunology +20

Herpes Simplex Virus Encephalitis in Human UNC-93B Deficiency

Armanda Casrouge, Shen‐Ying Zhang, Céline Eidenschenk et al. · Science · 2006 · 752 citations

Sporadic Viral Encephalitis, Immunodeficiencies, Viral Pathogenesis +17

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

Paul Bastard, Adrian Gervais, Tom Le Voyer et al. · Science Immunology · 2021 · 600 citations · Full text