Mary C. Collins

Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism

Stephen Jun Fei Chong, Kartini Iskandar, Jolin Xiao Hui Lai et al. · Nucleic Acids Research · 2020 · 63 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Hyperphosphorylation of BCL-2 family proteins underlies functional resistance to venetoclax in lymphoid malignancies

Stephen Jun Fei Chong, Fen Zhu, Olga Dashevsky et al. · Journal of Clinical Investigation · 2023 · 43 citations · Full text

Medicine, Molecular Biology, Oncology +16

Novel BCL-2 Inhibitor Lisaftoclax in Relapsed or Refractory Chronic Lymphocytic Leukemia and Other Hematologic Malignancies: First-in-Human Open-Label Trial

Sikander Ailawadhi, Zi Chen, Bo Huang et al. · Clinical Cancer Research · 2023 · 38 citations · Full text

Medicine, Oncology, Pharmacology +17

BH3 profiling identifies ruxolitinib as a promising partner for venetoclax to treat T-cell prolymphocytic leukemia

Charles Herbaux, Christoph Kornauth, Stéphanie Poulain et al. · Blood · 2021 · 37 citations · Full text

Medicine, Oncology, Pharmacology +11

First-in-Human Study with Preclinical Data of BCL-2/BCL-xL Inhibitor Pelcitoclax in Locally Advanced or Metastatic Solid Tumors

Nehal J. Lakhani, Drew Rasco, Hengbang Wang et al. · Clinical Cancer Research · 2023 · 24 citations

Medicine, Oncology, Pharmacology +16