Inhibition of cell proliferation by the somatostatin analogue RC-160 is mediated by somatostatin receptor subtypes SSTR2 and SSTR5 through different mechanisms.

Louis Buscail, J.P. Estève, Nathalie Saint‐Laurent, +7

Proceedings of the National Academy of Sciences

SclerostinSignal TransductionMolecular PhysiologySignaling PathwayMedicine +13

Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer.

Louis Buscail, Nathalie Saint‐Laurent, Eric Chastre, +6

PubMed

Sst2 ExpressionPancreatic CancerGastrointestinal OncologyMedicinePathology +12

The Tyrosine Phosphatase SHP-1 Associates with the sst2 Somatostatin Receptor and Is an Essential Component of sst2-mediated Inhibitory Growth Signaling

Frédéric Lopez, Jean‐Pierre Estève, Louis Buscail, +6

Journal of Biological Chemistry

Characterization of the antiproliferative signal mediated by the somatostatin receptor subtype sst5

Pierre Cordelier, Jean‐Pierre Estève, Corinne Bousquet, +6

Proceedings of the National Academy of Sciences

sst2 Somatostatin Receptor Mediates Cell Cycle Arrest and Induction of p27

Philippe Pagès, Naoual Benali, Nathalie Saint‐Laurent, +6

Journal of Biological Chemistry

Signal TransductionDevelopmental BiologyCell RegulationSignaling PathwayReceptor Tyrosine Kinase +12

Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238

Naoual Benali, Pierre Cordelier, Denis Calise, +9

Proceedings of the National Academy of Sciences

ImmunologyPathologyCancer BiologyTumor BiologyPancreatic Cancer +15

sst2 Somatostatin Receptor Mediates Negative Regulation of Insulin Receptor Signaling through the Tyrosine Phosphatase SHP-1

Corinne Bousquet, Nathalie Delesque, Frédéric Lopez, +6

Journal of Biological Chemistry

Src-family Tyrosine Kinases in Activation of ERK-1 and p85/p110-phosphatidylinositol 3-Kinase by G/CCKBReceptors

Laurence Daulhac, Aline Kowalski‐Chauvel, Lucien Pradayrol, +2

Journal of Biological Chemistry

Insulin ReceptorCellular PhysiologyInsulin SignalingSignaling PathwayCell Regulation +17

Direct Inhibitory Effects of a Somatostatin Analog, SMS 201-995, on AR4-2J Cell Proliferation via Pertussis Toxin-Sensitive Guanosine Triphosphate-Binding Protein-Independent Mechanism*

Nathalie Viguerie, N. Tahiri‐Jouti, Anne-Marie Ayral, +8

Endocrinology

Gene Therapy for Pancreatic Carcinoma: Local and Distant Antitumor Effects after Somatostatin Receptor sst2 Gene Transfer

Philippe Rochaix, Nathalie Delesque, J.P. Estève, +5

Human Gene Therapy

Tumor BiologyPancreatic CancerOncogenic AgentMedicineImmunology +13