Chi Xu

The metabolic ER stress sensor IRE1α suppresses alternative activation of macrophages and impairs energy expenditure in obesity

Bo Shan, Xiaoxia Wang, Ying Wu et al. · Nature Immunology · 2017 · 362 citations

Inflammation, Obesity, Metabolic Syndrome +14

BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes

Zhen Qi, Yehua Li, Bing Zhao et al. · Nature Communications · 2017 · 314 citations · Full text

HER2/EGFR–AKT Signaling Switches TGFβ from Inhibiting Cell Proliferation to Promoting Cell Migration in Breast Cancer

Fei Huang, Qiaoni Shi, Yuzhen Li et al. · Cancer Research · 2018 · 96 citations

A Systems Approach to Reverse Engineer Lifespan Extension by Dietary Restriction

Lei Hou, Dan Wang, Di Chen et al. · Cell Metabolism · 2016 · 70 citations · Full text

Caloric Restriction, Nutrition, Lifespan Extension +12

Liver X receptor activation attenuates inflammatory response and protects cholinergic neurons in APP/PS1 transgenic mice

Weigang Cui, Yan Sun, Zhijun Wang et al. · Neuroscience · 2012 · 55 citations

Inflammation, Signal Transduction, Medicine +15