Paul D. Smith

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

Adrian F. Hernandez, Jennifer B. Green, Salim Janmohamed et al. · The Lancet · 2018 · 1.7K citations · Full text

Diabetes Management, Cardiovascular Disease, Diabetes +6

Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study

Pasi A. Jänne, Alice T. Shaw, José Rodrigues Pereira et al. · The Lancet Oncology · 2012 · 654 citations

Non-small-cell Lung Cancer, Medicine, Metronomic Therapy +7

Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation

Annabelle Lewis, Kohzoh Mitsuya, David Umlauf et al. · Nature Genetics · 2004 · 413 citations

Chromatin, Developmental Biology, Epigenetic Change +10

AZD6244 (ARRY-142886), a potent inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1/2 kinases: mechanism of action <i>in vivo</i> , pharmacokinetic/pharmacodynamic relationship, and potential for combination in preclinical models

Barry R. Davies, Armelle Logié, Jennifer S. McKay et al. · Molecular Cancer Therapeutics · 2007 · 387 citations

Activity of the Monocarboxylate Transporter 1 Inhibitor AZD3965 in Small Cell Lung Cancer

Radosław Polański, Cassandra L. Hodgkinson, Alberto Fusi et al. · Clinical Cancer Research · 2013 · 345 citations · Full text