Nima Sharifi

Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer

Kai‐Hsiung Chang, Rui Li, Mahboubeh Papari-Zareei et al. · Proceedings of the National Academy of Sciences · 2011 · 338 citations

Medicine, Endocrinology, Oncology +17

A Gain-of-Function Mutation in DHT Synthesis in Castration-Resistant Prostate Cancer

Kai‐Hsiung Chang, Rui Li, Barbara Kuri et al. · Cell · 2013 · 313 citations · Full text

Medicine, Molecular Biology, Oncology +16

Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer

Zhenfei Li, Andrew C. Bishop, Mohammad Alyamani et al. · Nature · 2015 · 253 citations

Medicine, Oncology, Pharmacology +14

Effect of <i>SLCO1B3</i> Haplotype on Testosterone Transport and Clinical Outcome in Caucasian Patients with Androgen-Independent Prostatic Cancer

Akinobu Hamada, Tristan M. Sissung, Douglas K. Price et al. · Clinical Cancer Research · 2008 · 191 citations · Full text

Medicine, Endocrinology, Genetics +8

DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis

Jonathan F. Goodwin, Vishal Kothari, Justin M. Drake et al. · Cancer Cell · 2015 · 182 citations · Full text

Medicine, Molecular Biology, Oncology +14