Juan José Pérez Ruixo

Phase III Trial of Gemcitabine Plus Tipifarnib Compared With Gemcitabine Plus Placebo in Advanced Pancreatic Cancer

Eric Van Cutsem, Helgi van de Velde, Petr Karásek et al. · Journal of Clinical Oncology · 2004 · 774 citations · Full text

Medicine, Oncology, Pharmacology +12

Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics

Thi Huyen Tram Nguyen, Nicholas H. G. Holford, Nidal Al‐Huniti et al. · CPT Pharmacometrics & Systems Pharmacology · 2016 · 381 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +14

Phase III Double-Blind Placebo-Controlled Study of Farnesyl Transferase Inhibitor R115777 in Patients With Refractory Advanced Colorectal Cancer

Sheela Rao, David Cunningham, Armand de Gramont et al. · Journal of Clinical Oncology · 2004 · 239 citations · Full text

Medicine, Oncology, Pharmacology +16

Phase II Study of the Efficacy and Tolerability of Two Dosing Regimens of the Farnesyl Transferase Inhibitor, R115777, in Advanced Breast Cancer

Stephen R.D. Johnston, Tamas Hickish, Stephen Houston et al. · Journal of Clinical Oncology · 2003 · 196 citations

Medicine, Oncology, Pharmacology +16

Phase II and Pharmacodynamic Study of the Farnesyltransferase Inhibitor R115777 as Initial Therapy in Patients With Metastatic Pancreatic Adenocarcinoma

Steven J. Cohen, Linus Ho, Sulabha Ranganathan et al. · Journal of Clinical Oncology · 2003 · 171 citations

Medicine, Pharmacology, Pharmacotherapy +11