Aya Jakobovits

Functional transplant of megabase human immunoglobulin loci recapitulates human antibody response in mice

Michael J. Mendez, Larry L. Green, José R. F. Corvalán et al. · Nature Genetics · 1997 · 373 citations

Histocompatibility, Human Antibody Response, Immunogenetics +14

Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

Larry L. Green, Margaret C. Hardy, Catherine E. Maynard-Currie et al. · Nature Genetics · 1994 · 351 citations · Full text

Medicine, Immunology, Human Ig Heavy +7

STEAP: A prostate-specific cell-surface antigen highly expressed in human prostate tumors

René Hubert, Igor Vivanco, Emily Chen et al. · Proceedings of the National Academy of Sciences · 1999 · 350 citations · Full text

Prostate-specific Cell-surface Antigen, Urology, Ewing Sarcoma +12

Eradication of established tumors by a fully human monoclonal antibody to the epidermal growth factor receptor without concomitant chemotherapy.

Xiaodong Yang, Xiao‐Chi Jia, J R Corvalán et al. · PubMed · 1999 · 330 citations

Immunology, Growth Factor Alpha, Immunotherapy +16

Catalytic cleavage of the androgen-regulated TMPRSS2 protease results in its secretion by prostate and prostate cancer epithelia.

Daniel Afar, Igor Vivanco, René Hubert et al. · PubMed · 2001 · 285 citations

Signal Transduction, Tmprss2-encoded Serine Protease, Medicine +14