Hiroshi Kitani

Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling

Kento Imajo, Koji Fujita, Masato Yoneda et al. · Cell Metabolism · 2012 · 340 citations · Full text

Life Sciences, Endocrinology, Immunology +14

The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells

Takato Takenouchi, Masaaki Nakai, Yoshifumi Iwamaru et al. · The Journal of Immunology · 2009 · 126 citations · Full text

Life Sciences, Immunology, Pharmacology +13

Inhibitory effects of U73122 and U73343 on Ca influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line

Takato Takenouchi, Kazumasa Ogihara, Mitsuru Sato et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2005 · 125 citations

Life Sciences, Cell Biology, Pharmacology +17

Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-Like 4 Expression through AKT-mediated Activation of β-Catenin

Jianghui Zhang, Shigetomo Fukuhara, Keisuke Sako et al. · Journal of Biological Chemistry · 2011 · 115 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

γ-Irradiation induces P2X7 receptor-dependent ATP release from B16 melanoma cells

Yasuhiro Ohshima, Mitsutoshi Tsukimoto, Takato Takenouchi et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2009 · 102 citations

Medicine, Molecular Biology, Oncology +12