Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling

Kento Imajo, Koji Fujita, Masato Yoneda, +15

Cell Metabolism

InflammationHepatologyLow-dose EndotoxinLiver PhysiologyPhysiology +10

The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells

Takato Takenouchi, Masaaki Nakai, Yoshifumi Iwamaru, +9

The Journal of Immunology

MitophagyPrimary MicrogliaInnate Immune SystemImmunologyCell Death +18

Inhibitory effects of U73122 and U73343 on Ca influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line

Takato Takenouchi, Kazumasa Ogihara, Mitsuru Sato, +1

Biochimica et Biophysica Acta (BBA) - General Subjects

InflammationSignal TransductionMolecular PhysiologyP2x7 Nucleotide ReceptorsCell Signaling +11

Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-Like 4 Expression through AKT-mediated Activation of β-Catenin

Jianghui Zhang, Shigetomo Fukuhara, Keisuke Sako, +5

Journal of Biological Chemistry

γ-Irradiation induces P2X7 receptor-dependent ATP release from B16 melanoma cells

Yasuhiro Ohshima, Mitsutoshi Tsukimoto, Takato Takenouchi, +5

Biochimica et Biophysica Acta (BBA) - General Subjects

Signal TransductionCell RegulationMedicineB16 Melanoma CellsMelanoma +10

FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice

Takehiro Nakagaki, Katsuya Satoh, Daisuke Ishibashi, +10

Autophagy

A Role of N-Cadherin in Neuronal Differentiation of Embryonic Carcinoma P19 Cells

Xia Gao, Wei Bian, Jing Yang, +4

Biochemical and Biophysical Research Communications

Developmental BiologyGliomaNeuronal DifferentiationCell ProliferationTumor Suppressor +3

Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophages

Ayumi Kawano, Mitsutoshi Tsukimoto, Daisuke Mori, +5

Biochemical and Biophysical Research Communications

InflammationCytokineP2x4 ReceptorInflammatory DiseaseInflammatory Lung Disease +11

Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages

Ayumi Kawano, Mitsutoshi Tsukimoto, Taisei Noguchi, +5

Biochemical and Biophysical Research Communications

InflammationCytokineP2x4 ReceptorImmunologyAutophagy +8

Wnt-1 promotes neuronal differentiation and inhibits gliogenesis in P19 cells

Ke Tang, Jiali Yang, Xiang Gao, +5

Biochemical and Biophysical Research Communications

NeuroregenerationDevelopmental BiologyMolecular NeuroscienceP19 CellsNeural Stem Cell +6