Hiroshi Kitani

Hyperresponsivity to Low-Dose Endotoxin during Progression to Nonalcoholic Steatohepatitis Is Regulated by Leptin-Mediated Signaling

Kento Imajo, Koji Fujita, Masato Yoneda et al. · Cell Metabolism · 2012 · 334 citations · Full text

Inflammation, Hepatology, Low-dose Endotoxin +12

The Activation of P2X7 Receptor Impairs Lysosomal Functions and Stimulates the Release of Autophagolysosomes in Microglial Cells

Takato Takenouchi, Masaaki Nakai, Yoshifumi Iwamaru et al. · The Journal of Immunology · 2009 · 126 citations · Full text

Mitophagy, Primary Microglia, Innate Immune System +20

Inhibitory effects of U73122 and U73343 on Ca influx and pore formation induced by the activation of P2X7 nucleotide receptors in mouse microglial cell line

Takato Takenouchi, Kazumasa Ogihara, Mitsuru Sato et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2005 · 121 citations

Inflammation, Signal Transduction, Molecular Physiology +13

Angiopoietin-1/Tie2 Signal Augments Basal Notch Signal Controlling Vascular Quiescence by Inducing Delta-Like 4 Expression through AKT-mediated Activation of β-Catenin

Jianghui Zhang, Shigetomo Fukuhara, Keisuke Sako et al. · Journal of Biological Chemistry · 2011 · 115 citations · Full text

γ-Irradiation induces P2X7 receptor-dependent ATP release from B16 melanoma cells

Yasuhiro Ohshima, Mitsutoshi Tsukimoto, Takato Takenouchi et al. · Biochimica et Biophysica Acta (BBA) - General Subjects · 2009 · 102 citations

Signal Transduction, Cell Regulation, Medicine +12