Joseph L. Witztum

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

Seppo Ylä‐Herttuala, Wulf Palinski, Michael E. Rosenfeld et al. · Journal of Clinical Investigation · 1989 · 1.9K citations · Full text

Vascular Disease, Pathology, Hyperlipidemia +19

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

Urs P. Steinbrecher, Srinivasan Parthasarathy, David S. Leake et al. · Proceedings of the National Academy of Sciences · 1984 · 1.6K citations · Full text

Endothelial Cells, Lipid Peroxidation, Cu2+ Concentration +17

Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.

Claudio Napoli, Francesco Paolo D’Armiento, Francesco Paolo Mancini et al. · Journal of Clinical Investigation · 1997 · 986 citations · Full text

Hyperlipidemia, Oxidative Stress, Metabolic Syndrome +16

Lipoprotein(a) Reduction in Persons with Cardiovascular Disease

Sotirios Tsimikas, Ewa Karwatowska‐Prokopczuk, Ioanna Gouni‐Berthold et al. · New England Journal of Medicine · 2020 · 924 citations · Full text

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

Seppo Ylä‐Herttuala, Beth Lipton, Michael E. Rosenfeld et al. · Proceedings of the National Academy of Sciences · 1991 · 877 citations · Full text

Vascular Disease, Immunology, Pathology +17