Carolann Espy

Safer non-viral DNA delivery using lipid nanoparticles loaded with endogenous anti-inflammatory lipids

Manthan N. Patel, Sachchidanand Tiwari, Yufei Wang et al. · Nature Biotechnology · 2025 · 57 citations · Full text

Pharmacy, Pharmaceutical Biotechnology, Pharmaceutics +16

Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape

Serena Omo‐Lamai, Yufei Wang, Manthan N. Patel et al. · Nature Nanotechnology · 2025 · 55 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects

Serena Omo‐Lamai, Yufei Wang, Manthan N. Patel et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2024 · 50 citations · Full text

Life Sciences, Molecular Biology, Pharmaceutics +17

Marginated Neutrophils in the Lungs Effectively Compete for Nanoparticles Targeted to the Endothelium, Serving as a Part of the Reticuloendothelial System

Marco E. Zamora, Eno‐Obong Essien, Kartik Bhamidipati et al. · ACS Nano · 2024 · 25 citations · Full text

Life Sciences, Immunology, Pharmaceutics +17

Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains

Lin Guo, Jacob R. Mann, Jocelyn C. Mauna et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 14 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +17