C. R. Weber

Cloning of the gene for spinocerebellar ataxia 2 reveals a locus with high sensitivity to expanded CAG/glutamine repeats

Georges Imbert, Frédéric Saudou, Gaël Yvert et al. · Nature Genetics · 1996 · 846 citations

Molecular Neuroscience, Spinocerebellar Ataxia 2, High Sensitivity +11

Cloning of the SCA7 gene reveals a highly unstable CAG repeat expansion

Gilles David, Nacer Abbas, Giovanni Stévanin et al. · Nature Genetics · 1997 · 769 citations

Sca7 Gene, Molecular Research, Natural Sciences +5

Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias

Yvon Trottier, Yves Lutz, Giovanni Stévanin et al. · Nature · 1995 · 653 citations

Pathological Epitope, Degenerative Disease, Dominant Cerebellar Ataxias +8

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

Yvon Trottier, Didier Devys, Georges Imbert et al. · Nature Genetics · 1995 · 445 citations

Knockout Mouse, Disease Protein, Genetics +5

Proteases Acting on Mutant Huntingtin Generate Cleaved Products that Differentially Build Up Cytoplasmic and Nuclear Inclusions

Astrid Lunkes, Katrin S. Lindenberg, Léa Ben-Haı̈em et al. · Molecular Cell · 2002 · 415 citations · Full text

Protein Function, Protein Expression, Natural Sciences +7