Sean J. McIlwain

A three-dimensional model of the yeast genome

Zhijun Duan, Mirela Andronescu, Kevin Schutz et al. · Nature · 2010 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Top-Down Proteomics of Large Proteins up to 223 kDa Enabled by Serial Size Exclusion Chromatography Strategy

Wenxuan Cai, Trisha Tucholski, Bifan Chen et al. · Analytical Chemistry · 2017 · 131 citations

Life Sciences, Biochemistry, Molecular Biology +15

Forazoline A: Marine‐Derived Polyketide with Antifungal In Vivo Efficacy

Thomas P. Wyche, Jeff S. Piotrowski, Yanpeng Hou et al. · Angewandte Chemie International Edition · 2014 · 117 citations · Full text

Life Sciences, Medicinal Chemistry, Microbiology +17

Directed Evolution Reveals Unexpected Epistatic Interactions That Alter Metabolic Regulation and Enable Anaerobic Xylose Use by Saccharomyces cerevisiae

Trey K. Sato, Mary Tremaine, Lucas S. Parreiras et al. · PLoS Genetics · 2016 · 111 citations · Full text

Life Sciences, Biology, Genetics +17

Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

Trisha Tucholski, Wenxuan Cai, Zachery R. Gregorich et al. · Proceedings of the National Academy of Sciences · 2020 · 110 citations · Full text

Life Sciences, Cardiology, Molecular Biology +16