John Mansfield

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

Miles Parkes, Jeffrey C. Barrett, Natalie J. Prescott et al. · Nature Genetics · 2007 · 1.2K citations · Full text

Chronic Inflammatory Diseases, Disease Susceptibility, Cell Autophagy +13

Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

Isabelle Cleynen, Gabrielle Boucher, Luke Jostins et al. · The Lancet · 2015 · 750 citations · Full text

The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease

Andrew Cuthbert, Sheila Fisher, Muddassar M. Mirza et al. · Gastroenterology · 2002 · 690 citations

Inflammation, Nod2 Gene Mutations, Autoimmune Disease +8

Predictors of anti-TNF treatment failure in anti-TNF-naive patients with active luminal Crohn's disease: a prospective, multicentre, cohort study

Nicholas A. Kennedy, Graham Heap, Harry Green et al. · ˜The œLancet. Gastroenterology & hepatology · 2019 · 655 citations · Full text

Inflammation, Active Luminal Crohn, Anti-tnf Treatment Failure +9

Etrolizumab as induction therapy for ulcerative colitis: a randomised, controlled, phase 2 trial

Séverine Vermeire, Sharon O’Byrne, Mary Keir et al. · The Lancet · 2014 · 449 citations · Full text