Inhibition of TRPC6 Channel Activity Contributes to the Antihypertrophic Effects of Natriuretic Peptides-Guanylyl Cyclase-A Signaling in the Heart

Hideyuki Kinoshita, Koichiro Kuwahara, Motohiro Nishida, +15

Circulation Research

Reciprocal expression of MRTF‐A and myocardin is crucial for pathological vascular remodelling in mice

Takeya Minami, Koichiro Kuwahara, Yasuaki Nakagawa, +19

The EMBO Journal

Overexpression of Brain Natriuretic Peptide Facilitates Neutrophil Infiltration and Cardiac Matrix Metalloproteinase-9 Expression After Acute Myocardial Infarction

Rika Kawakami, Yoshihiko Saito, Ichiro Kishimoto, +13

Circulation

Myocardin-Related Transcription Factor A Is a Common Mediator of Mechanical Stress- and Neurohumoral Stimulation-Induced Cardiac Hypertrophic Signaling Leading to Activation of Brain Natriuretic Peptide Gene Expression

Koichiro Kuwahara, Hideyuki Kinoshita, Yoshihiro Kuwabara, +6

Molecular and Cellular Biology

Cardiac MuscleCommon MediatorCardiovascular FunctionCellular PhysiologyNuclear Translocation +17

Angiotensin II Type 2 Receptor Deficiency Exacerbates Heart Failure and Reduces Survival After Acute Myocardial Infarction in Mice

Yuichiro Adachi, Yoshihiko Saito, Ichiro Kishimoto, +13

Circulation

Increased Expression of HCN Channels in the Ventricular Myocardium Contributes to Enhanced Arrhythmicity in Mouse Failing Hearts

Yoshihiro Kuwabara, Koichiro Kuwahara, Makoto Takano, +14

Journal of the American Heart Association

Role of Natriuretic Peptide Receptor Guanylyl Cyclase-A in Myocardial Infarction Evaluated Using Genetically Engineered Mice

Michio Nakanishi, Yoshihiko Saito, Ichiro Kishimoto, +13

Hypertension

Molecular PharmacologyCardiomyopathyHeart FailureCardiovascular DiseaseMedicine +11

Hypertrophic responses to cardiotrophin-1 are not mediated by STAT3, but via a MEK5-ERK5 pathway in cultured cardiomyocytes

Nobuki Takahashi, Yoshihiko Saito, Koichiro Kuwahara, +9

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathySignal TransductionMolecular PhysiologyMek5-erk5 Pathway +8

Class II HDACs mediate CaMK-dependent signaling to NRSF in ventricular myocytes

Yasuaki Nakagawa, Koichiro Kuwahara, Masaki Harada, +10

Journal of Molecular and Cellular Cardiology

Cardiac MuscleCardiomyopathyMolecular PhysiologySignal TransductionPhysiology +9

Angiotensin <scp>II</scp> type 1a receptor signalling directly contributes to the increased arrhythmogenicity in cardiac hypertrophy

Shinji Yasuno, Koichiro Kuwahara, Hideyuki Kinoshita, +8

British Journal of Pharmacology