Daniel M. C. Schwarz

Temperature-jump solution X-ray scattering reveals distinct motions in a dynamic enzyme

Michael C. Thompson, Benjamin A. Barad, Alexander M. Wolff et al. · Nature Chemistry · 2019 · 93 citations · Full text

Life Sciences, Biochemistry, Biophysics +12

Hsp70 and Hsp40 inhibit an inter-domain interaction necessary for transcriptional activity in the androgen receptor

Bahareh Eftekharzadeh, Varuna C. Banduseela, Giulio Chiesa et al. · Nature Communications · 2019 · 86 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Design, Synthesis, and Evaluation of Nonretinoid Retinol Binding Protein 4 Antagonists for the Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease

Christopher L. Cioffi, Nicoleta Dobri, Emily Freeman et al. · Journal of Medicinal Chemistry · 2014 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Bicyclic [3.3.0]-Octahydrocyclopenta[<i>c</i>]pyrrolo Antagonists of Retinol Binding Protein 4: Potential Treatment of Atrophic Age-Related Macular Degeneration and Stargardt Disease

Christopher L. Cioffi, Bóglárka Rácz, Emily Freeman et al. · Journal of Medicinal Chemistry · 2015 · 32 citations · Full text

Health Professions, Medicinal Chemistry, Pharmacology +13

Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance

David Mavor, Kyle A. Barlow, Daniel Asarnow et al. · Biology Open · 2018 · 29 citations · Full text

Life Sciences, Biology, Molecular Biology +16