Chenhe Liu

Discovery of coumarin derivatives as potent and selective cyclin-dependent kinase 9 (CDK9) inhibitors with high antitumour activity

Junyu Xu, Hongmei Li, Xinren Wang et al. · European Journal of Medicinal Chemistry · 2020 · 42 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Identification of <i>N</i>-Phenyl-7<i>H</i>-pyrrolo[2,3-<i>d</i>]pyrimidin-4-amine Derivatives as Novel, Potent, and Selective NF-κB Inducing Kinase (NIK) Inhibitors for the Treatment of Psoriasis

Yuqin Zhu, Yuxiang Ma, Weidong Zu et al. · Journal of Medicinal Chemistry · 2020 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of <i>N</i>-(4-(3-isopropyl-2-methyl-2<i>H</i>-indazol-5-yl)pyrimidin-2-yl)-4-(4-methylpiperazin-1-yl)quinazolin-7-amine as a Novel, Potent, and Oral Cyclin-Dependent Kinase Inhibitor against Haematological Malignancies

Jianhang Huang, Xinren Wang, Ruinan Dong et al. · Journal of Medicinal Chemistry · 2021 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

The discovery of quinoline derivatives, as NF-κB inducing kinase (NIK) inhibitors with anti-inflammatory effects in vitro, low toxicities against T cell growth

Jianing Song, Yuqin Zhu, Weidong Zu et al. · Bioorganic & Medicinal Chemistry · 2020 · 15 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11