Identifying pre-disease signals before metabolic syndrome in mice by dynamical network biomarkers

Keiichi Koizumi, Makito Oku, Shusaku Hayashi, +8

Scientific Reports

Metabolic DisorderDynamical Network BiomarkersPre-disease SignalsObesityMetabolic Syndrome +22

CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-α-induced apoptosis by tumor-associated macrophages

Ji‐Ye Kee, Aya Ito, Shozo Hojo, +13

BMC Cancer

Partial depletion of CD206-positive M2-like macrophages induces proliferation of beige progenitors and enhances browning after cold stimulation

Yoshiko Igarashi, Allah Nawaz, Tomonobu Kado, +12

Scientific Reports

Shikonin induces an anti‑tumor effect on murine mammary cancer via p38‑dependent apoptosis

Jiuxiang Xu, Keiichi Koizumi, Mengxin Liu, +7

Oncology Reports

The Long-Term Effects of a Kampo Medicine, Juzentaihoto, on Maintenance of Antibody Titer in Elderly People after Influenza Vaccination

Ikuo Saiki, Keiichi Koizumi, Hirozo Goto, +14

Evidence-based Complementary and Alternative Medicine

Suppression of Dynamical Network Biomarker Signals at the Predisease State (<i>Mibyou</i>) before Metabolic Syndrome in Mice by a Traditional Japanese Medicine (Kampo Formula) Bofutsushosan

Keiichi Koizumi, Makito Oku, Shusaku Hayashi, +8

Evidence-based Complementary and Alternative Medicine

Gomisin N enhances TNF-α-induced apoptosis via inhibition of the NF-κB and EGFR survival pathways

Pornthip Waiwut, Myoung‐Sook Shin, Akiko Inujima, +4

Molecular and Cellular Biochemistry

InflammationEgfr Survival PathwaysCytokineGomisin NSignaling Pathway +11

Discovery of a sugar-based nanoparticle universally existing in boiling herbal water extracts and their immunostimulant effect

Hirofumi Iitsuka, Keiichi Koizumi, Akiko Inujima, +14

Biochemistry and Biophysics Reports

NanoparticlesInflammationInflammatory CytokinesAnti-inflammatoryElectron Microscopy +13

Inhibitory effect of Moutan Cortex aqueous fraction on mast cell-mediated allergic inflammation

Ji‐Ye Kee, Akiko Inujima, Tsugunobu Andoh, +7

Journal of Natural Medicines

InflammationAsthmaAutoimmune DiseaseAllergyAtopic Dermatitis +8

Immune adjuvant effect of Juzentaihoto, a Japanese traditional herbal medicine, on tumor vaccine therapy in a mouse model

Nobuhiro Takeno, Akiko Inujima, Kanna Shinohara, +5

International Journal of Oncology

ImmunologyImmunoeditingImmunotherapeuticsImmunotherapyTumor Immunology +19