James M. Holton

Femtosecond X-ray protein nanocrystallography

Henry N. Chapman, Petra Fromme, Anton Barty et al. · Nature · 2011 · 2.1K citations · Full text

Natural Sciences, Biophysics, Physics +16

Structures of the Bacterial Ribosome at 3.5 A Resolution

B.S. Schuwirth, M.A. Borovinskaya, C.W. Hau et al. · Science · 2005 · 1.4K citations · Full text

Life Sciences, Biophysics, Microbiology +14

Large language models generate functional protein sequences across diverse families

Ali Madani, Ben Krause, Eric R. Greene et al. · Nature Biotechnology · 2023 · 1.1K citations · Full text

Computing, Bioinformatics, Computer Science +16

Accessing protein conformational ensembles using room-temperature X-ray crystallography

James S. Fraser, Henry van den Bedem, Avi J. Samelson et al. · Proceedings of the National Academy of Sciences · 2011 · 652 citations

Life Sciences, Biochemistry, Biophysics +17

Structures of the intermediates of Kok’s photosynthetic water oxidation clock

Jan Kern, Ruchira Chatterjee, I.D. Young et al. · Nature · 2018 · 527 citations · Full text

Life Sciences, Biochemistry, Plant Biology +14