Two Phase 3 Trials of Dupilumab versus Placebo in Atopic Dermatitis

Eric L. Simpson, Thomas Bieber, Emma Guttman‐Yassky, +22

New England Journal of Medicine

Dupilumab Treatment in Adults with Moderate-to-Severe Atopic Dermatitis

Lisa A. Beck, Diamant Thaçi, Jennifer D. Hamilton, +16

New England Journal of Medicine

Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

Emma Guttman‐Yassky, Robert Bissonnette, Benjamin Ungar, +17

Journal of Allergy and Clinical Immunology

Efficacy and safety of dupilumab in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical treatments: a randomised, placebo-controlled, dose-ranging phase 2b trial

Diamant Thaçi, Eric L. Simpson, Lisa A. Beck, +18

The Lancet

AllergyAtopic DermatitisAllergy MedicineModerate-to-severe Atopic DermatitisSkin Allergy +5

Conjunctivitis in dupilumab clinical trials

Bolanle Akinlade, Emma Guttman‐Yassky, Marjolein de Bruin‐Weller, +25

British Journal of Dermatology

Peak Pruritus Numerical Rating Scale: psychometric validation and responder definition for assessing itch in moderate‐to‐severe atopic dermatitis

Gil Yosipovitch, Matthew Reaney, Vera Mastey, +14

British Journal of Dermatology

Patient burden of moderate to severe atopic dermatitis (AD): Insights from a phase 2b clinical trial of dupilumab in adults

Eric L. Simpson, Thomas Bieber, Laurent Eckert, +5

Journal of the American Academy of Dermatology

Dupilumab shows long-term safety and efficacy in patients with moderate to severe atopic dermatitis enrolled in a phase 3 open-label extension study

Mette Deleuran, Diamant Thaçi, Lisa A. Beck, +24

Journal of the American Academy of Dermatology

A basophil-neuronal axis promotes itch

Fang Wang, Anna M. Trier, Fengxian Li, +21

Cell

AllergyGranulocyteNeurotransmitterNeuroscienceNervous System +4

IL-4Rα Blockade by Dupilumab Decreases Staphylococcus aureus Colonization and Increases Microbial Diversity in Atopic Dermatitis

Chris Callewaert, Teruaki Nakatsuji, Rob Knight, +14

Journal of Investigative Dermatology